The Anti-Tumor and Immunomodulatory Effects of PLGA-Based Docetaxel Nanoparticles in Lung Cancer: The Potential Involvement of Necroptotic Cell Death through Reactive Oxygen Species and Calcium Build-Up

The Anti-Tumor and Immunomodulatory Effects of PLGA-Based Docetaxel Nanoparticles in Lung Cancer: The Potential Involvement of Necroptotic Cell Death through Reactive Oxygen Species and Calcium Build-Up

Taxanes, microtubule stabilizing agents, are extensively used in the treatment of non-small cell lung cancer (NSCLC). However, their clinical effectiveness remains restricted owing to significant adverse effects and drug resistance. Nanotechnology may guide chemotherapeutic drugs directly and select...

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Bibliographic Details
Main Authors: Parul Gupta, Arpita Singh, Ajay Kumar Verma, Surya Kant, Anuj Kumar Pandey, Puneet Khare, Ved Prakash
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Vaccines
Subjects:
docetaxel
plga
inflammatory response
calcium build-up
Online Access:https://www.mdpi.com/2076-393X/10/11/1801

Internet

https://www.mdpi.com/2076-393X/10/11/1801

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