High frequency of BRCA recurrent mutations in a consecutive series of unselected ovarian cancer patients

High frequency of BRCA recurrent mutations in a consecutive series of unselected ovarian cancer patients

Hereditary predisposition to breast and ovarian cancer (HBOC) is diagnosed by molecular analysis of deleterious mutations in BRCA genes, allowing oncogenetic follow-up of patients and of their families. BRCA testing addresses only to HBOC families, using restrictive inclusion criteria based on famil...

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Bibliographic Details
Main Authors: Chicos Andrei, Negura Lucian, Braescu Rares, Morariu Aliona, Negura Anca, Chicos Andreea, Lupascu Cristian
Format: Article
Language:English
Published: Sciendo 2020-07-01
Series:Romanian Journal of Laboratory Medicine
Subjects:
ovarian cancer
hereditary predisposition
brca genes
recurrent mutations
Online Access:https://doi.org/10.2478/rrlm-2020-0026

Internet

https://doi.org/10.2478/rrlm-2020-0026

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