Partial proteasomal degradation of Lola triggers the male-to-female switch of a dimorphic courtship circuit
It is unclear how some Drosophila neurons develop sex-specific neurites that contribute to dimorphic circuitries required for gendered behavior. The authors show that sex-specific cleavage by the E3 ubiquitin ligase Cullin1 and 26S proteasome of the pleiotropic BTB-ZF transcription factor Lola confe...
Main Authors: | Kosei Sato, Hiroki Ito, Atsushi Yokoyama, Gakuta Toba, Daisuke Yamamoto |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2019-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-08146-1 |
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