Cis-regulatory CYP6P9b P450 variants associated with loss of insecticide-treated bed net efficacy against Anopheles funestus

Bed nets treated with insecticides have been instrumental in reducing malaria mortality, but insecticide resistance is on the rise. Here, Mugenzi et al. identify genetic variants in the P450 gene CYP6P9b of Anopheles funestus that associate with insecticide resistance and develop a PCR-based diagnos...

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Bibliographic Details
Main Authors: Leon M. J. Mugenzi, Benjamin D. Menze, Magellan Tchouakui, Murielle J. Wondji, Helen Irving, Micareme Tchoupo, Jack Hearn, Gareth D. Weedall, Jacob M. Riveron, Charles S. Wondji
Format: Article
Language:English
Published: Nature Portfolio 2019-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12686-5