Phenyl-2-aminoethyl selenide ameliorates hippocampal long-term potentiation and cognitive deficits following doxorubicin treatment.

Phenyl-2-aminoethyl selenide ameliorates hippocampal long-term potentiation and cognitive deficits following doxorubicin treatment.

Chemotherapy-induced memory loss ("chemobrain") can occur following treatment with the widely used chemotherapeutic agent doxorubicin (DOX). However, the mechanisms through which DOX induces cognitive dysfunction are not clear, and there are no commercially available therapies for its trea...

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Bibliographic Details
Main Authors: Ahmad H Alhowail, Matthew Eggert, Jenna Bloemer, Priyanka D Pinky, Lauren Woodie, Subhrajit Bhattacharya, Dwipayan Bhattacharya, Manal A Buabeid, Bruce Smith, Muralikrishnan Dhanasekaran, Gary Piazza, Miranda N Reed, Martha Escobar, Robert D Arnold, Vishnu Suppiramaniam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0294280

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https://doi.org/10.1371/journal.pone.0294280

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