Heterogeneous activation of the TGFβ pathway in glioblastomas identified by gene expression-based classification using TGFβ-responsive genes

<p>Abstract</p> <p>Background</p> <p>TGFβ has emerged as an attractive target for the therapeutic intervention of glioblastomas. Aberrant TGFβ overproduction in glioblastoma and other high-grade gliomas has been reported, however, to date, none of these reports has syst...

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Bibliographic Details
Main Authors: Xu Xie L, Kapoun Ann M
Format: Article
Language:English
Published: BMC 2009-02-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/7/1/12