Blood–Brain Barrier Dysfunction in a 3D In Vitro Model of Alzheimer's Disease

Abstract Harmful materials in the blood are prevented from entering the healthy brain by a highly selective blood–brain barrier (BBB), and impairment of barrier function has been associated with a variety of neurological diseases. In Alzheimer's disease (AD), BBB breakdown has been shown to occ...

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Bibliographic Details
Main Authors: Yoojin Shin, Se Hoon Choi, Eunhee Kim, Enjana Bylykbashi, Jeong Ah Kim, Seok Chung, Doo Yeon Kim, Roger D. Kamm, Rudolph E. Tanzi
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.201900962