Subtleties in Clathrin heavy chain binding boxes provide selectivity among adaptor proteins of budding yeast
Abstract Clathrin forms a triskelion, or three-legged, network that regulates cellular processes by facilitating cargo internalization and trafficking in eukaryotes. Its N-terminal domain is crucial for interacting with adaptor proteins, which link clathrin to the membrane and engage with specific c...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-54037-z |