Polo-like kinase 1 is related with malignant characteristics and inhibits macrophages infiltration in glioma

Polo-like kinase 1 is related with malignant characteristics and inhibits macrophages infiltration in glioma

BackgroundTumor immune microenvironment (TIM) plays a critical role in tumorigenesis and progression. Recently, therapies based on modulating TIM have made great breakthroughs in cancer treatment. Polo-like kinase 1 (PLK1) is a crucial regulatory factor of the cell cycle process and its dysregulatio...

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Bibliographic Details
Main Authors: Lin Luo, Xiao-Yang Zhang, Ying-Wei Zhen, Gao-Chao Guo, Da-Zhao Peng, Cheng Wei, Dong-Ling Pei, Bin Yu, Yu-Chen Ji, Xian-Zhi Liu, Lei Han, Zhen-Yu Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
plk1
glioma
tumor immune microenvironment
immune infiltration
macrophages
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1058036/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.1058036/full

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