Polo-like kinase 1 is related with malignant characteristics and inhibits macrophages infiltration in glioma
BackgroundTumor immune microenvironment (TIM) plays a critical role in tumorigenesis and progression. Recently, therapies based on modulating TIM have made great breakthroughs in cancer treatment. Polo-like kinase 1 (PLK1) is a crucial regulatory factor of the cell cycle process and its dysregulatio...
Main Authors: | Lin Luo, Xiao-Yang Zhang, Ying-Wei Zhen, Gao-Chao Guo, Da-Zhao Peng, Cheng Wei, Dong-Ling Pei, Bin Yu, Yu-Chen Ji, Xian-Zhi Liu, Lei Han, Zhen-Yu Zhang |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-12-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.1058036/full |
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