Advancing Epidemiology and Genetic Approaches for the Treatment of Spinal and Bulbar Muscular Atrophy: Focus on Prevalence in the Indigenous Population of Western Canada

Advancing Epidemiology and Genetic Approaches for the Treatment of Spinal and Bulbar Muscular Atrophy: Focus on Prevalence in the Indigenous Population of Western Canada

Spinal and bulbar muscular atrophy (SBMA), also known as Kennedy’s disease, is a debilitating neuromuscular disease characterized by progressive muscular weakness and neuronal degeneration, affecting 1–2 individuals per 100,000 globally. While SBMA is relatively rare, recent studies have shown a sig...

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Bibliographic Details
Main Authors: Harry Wilton-Clark, Ammar Al-aghbari, Jessica Yang, Toshifumi Yokota
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Genes
Subjects:
spinal and bulbar muscular atrophy
antisense therapy
oligonucleotide
splice switching
mRNA knockdown
androgen receptor
Online Access:https://www.mdpi.com/2073-4425/14/8/1634

Internet

https://www.mdpi.com/2073-4425/14/8/1634

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