Effects of SGLT2-inhibitor on The Expression of MicroRNA-21, Transforming Growth Factor-β1, and Matrix Metalloproteinase-2 in The Process of Cardiac Fibrosis in Hyperglycemic Model Rats

BACKGROUND: Sodium glucose co-transporter-2 inhibitor (SGLT2-i), a new oral antidiabetic drug, has been recommended for its morbidity and mortality benefits in patients with heart failure. This study aimed to determine the effect of acute SGLT2-i therapy on the relative ratio expression of microRNA-...

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Bibliographic Details
Main Authors: Muhammad Ridwan, Herlina Dimiati, Maimun Syukri, Ronny Lesmana, Lia Meuthia Zaini
Format: Article
Language:English
Published: Secretariat of The Indonesian Biomedical Journal 2024-02-01
Series:Indonesian Biomedical Journal
Online Access:https://inabj.org/index.php/ibj/article/view/2776