Recovery of organ-specific tissue oxygen delivery at restrictive transfusion thresholds after fluid treatment in ovine haemorrhagic shock

Abstract Background Fluid resuscitation is the standard treatment to restore circulating blood volume and pressure after massive haemorrhage and shock. Packed red blood cells (PRBC) are transfused to restore haemoglobin levels. Restoration of microcirculatory flow and tissue oxygen delivery is criti...

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Bibliographic Details
Main Authors: Wayne B. Dyer, Gabriela Simonova, Sara Chiaretti, Mahe Bouquet, Rebecca Wellburn, Silver Heinsar, Carmen Ainola, Karin Wildi, Kei Sato, Samantha Livingstone, Jacky Y. Suen, David O. Irving, John-Paul Tung, Gianluigi li Bassi, John F. Fraser
Format: Article
Language:English
Published: SpringerOpen 2022-04-01
Series:Intensive Care Medicine Experimental
Subjects:
Online Access:https://doi.org/10.1186/s40635-022-00439-6