Spatial transcriptomics and in situ immune cell profiling of the host ectocervical landscape of HIV infected Kenyan sex working women

Spatial transcriptomics and in situ immune cell profiling of the host ectocervical landscape of HIV infected Kenyan sex working women

IntroductionChronic immune activation is a hallmark of human immunodeficiency virus (HIV) infection that significantly impacts disease pathogenesis. However, in-depth studies characterizing the immunological landscape of the ectocervix during chronic HIV infection remain scarce despite the importanc...

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Detalhes bibliográficos
Principais autores: Mathias Franzén Boger, Vilde Kaldhusdal, Anna Pascual-Reguant, Sandy Kroh, Ralf Uecker, Adam D. Burgener, Julie Lajoie, Kenneth Omollo, Joshua Kimani, Keith R. Fowke, Anja E. Hauser, Annelie Tjernlund, Kristina Broliden
Formato: Artigo
Idioma:English
Publicado em: Frontiers Media S.A. 2024-12-01
coleção:Frontiers in Immunology
Assuntos:
HIV
spatial transcriptomics
multi-epitope ligand cartography
mucosal immunology
T cells
B cells
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1483346/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1483346/full

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