Copper Modulates the Catalytic Activity of Protein Kinase CK2

Copper Modulates the Catalytic Activity of Protein Kinase CK2

Casein kinase 2 (CK2) is an evolutionarily conserved serine/threonine kinase implicated in a wide range of cellular functions and known to be dysregulated in various diseases such as cancer. Compared to most other kinases, CK2 exhibits several unusual properties, including dual co-substrate specific...

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Bibliographic Details
Main Authors: John E. Chojnowski, Rongrong Li, Tiffany Tsang, Fatimah H. Alfaran, Alexej Dick, Simon Cocklin, Donita C. Brady, Todd I. Strochlic
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
casein kinase 2 (CK2)
copper
cell signaling
protein kinase (CK2)
phosphorylation
kinase regulation
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.878652/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.878652/full

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