Treatment-emergent and trajectory-based peripheral gene expression markers of antidepressant response

Abstract Identifying biomarkers of antidepressant response may advance personalized treatment of major depressive disorder (MDD). We aimed to identify longitudinal changes in gene expression associated with response to antidepressants in a sample of MDD patients treated with escitalopram. Patients (...

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Bibliographic Details
Main Authors: Laura M. Fiori, Massimiliano Orri, Zahia Aouabed, Jean François Théroux, Rixing Lin, Corina Nagy, Benicio N. Frey, Raymond W. Lam, Glenda M. MacQueen, Roumen Milev, Daniel J. Müller, Sagar V. Parikh, Susan Rotzinger, Rudolf Uher, Jane A. Foster, Sidney H. Kennedy, Gustavo Turecki
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01564-8