The affinity purification and characterization of ATP synthase complexes from mitochondria

The mitochondrial F1-ATPase inhibitor protein, IF1, inhibits the hydrolytic, but not the synthetic activity of the F-ATP synthase, and requires the hydrolysis of ATP to form the inhibited complex. In this complex, the α-helical inhibitory region of the bound IF1 occupies a deep cleft in one of the t...

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Bibliographic Details
Main Authors: Michael J. Runswick, John V. Bason, Martin G. Montgomery, Graham C. Robinson, Ian M. Fearnley, John E. Walker
Format: Article
Language:English
Published: The Royal Society 2013-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.120160