Associations of HLA-A and HLA-B with vancomycin-induced drug reaction with eosinophilia and systemic symptoms in the Han-Chinese population

Associations of HLA-A and HLA-B with vancomycin-induced drug reaction with eosinophilia and systemic symptoms in the Han-Chinese population

Vancomycin is a commonly used antibiotic; however, it can cause life-threatening severe cutaneous adverse reactions, such as drug reaction with eosinophilia and systemic symptoms (DRESS). A previous study has reported a strong association between HLA-A*32:01 and vancomycin-induced DRESS in European...

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Bibliographic Details
Main Authors: Chuang-Wei Wang, Wei-Chen Lin, Wei-Ti Chen, Chun-Bing Chen, Chun-Wei Lu, Hsin-Han Hou, Rosaline Chung-Yee Hui, Jennifer Wu, Chih-Jung Chang, Ya-Ching Chang, Wen-Hung Chung, Taiwan Severe Cutaneous Adverse Reaction Consortium
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Pharmacology
Subjects:
severe cutaneous adverse drug reactions
drug reaction with eosinophilia and systematic symptoms
HLA
vancomycin
delayed-type drug hypersensitivity reactions
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.954596/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.954596/full

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