Human Telomeres Are Tethered to the Nuclear Envelope during Postmitotic Nuclear Assembly

Telomeres are essential for nuclear organization in yeast and during meiosis in mice. Exploring telomere dynamics in living human cells by advanced time-lapse confocal microscopy allowed us to evaluate the spatial distribution of telomeres within the nuclear volume. We discovered an unambiguous enri...

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Bibliographic Details
Main Authors: Laure Crabbe, Anthony J. Cesare, James M. Kasuboski, James A.J. Fitzpatrick, Jan Karlseder
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712004160