Therapeutic potential of a prominent dihydroxyflavanone pinocembrin for osteolytic bone disease: In vitro and in vivo evidence

Background/objective: As the pivotal cellular mediators of bone resorption and pathological bone remodeling, osteoclasts have emerged as a prominent target for anti-resorptive interventions. Pinocembrin (PIN), a predominant flavonoid found in damiana, honey, fingerroot, and propolis, has been recogn...

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Bibliographic Details
Main Authors: Guoju Hong, Shuqiang Li, Guanqiang Zheng, Xiaoxia Zheng, Qunzhang Zhan, Lin Zhou, Qiushi Wei, Wei He, Zhenqiu Chen
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Journal of Orthopaedic Translation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X24000032