Endothelial nitric oxide synthase alterations are independent of turbulence in the aorta of patients with a unicuspid aortic valveCentral MessagePerspective

Endothelial nitric oxide synthase alterations are independent of turbulence in the aorta of patients with a unicuspid aortic valveCentral MessagePerspective

Objectives: Certain aortic valve malformations predispose to ascending aortic aneurysm, although the mechanisms are incompletely understood. The aim of this study was to determine whether turbulence across the unicuspid aortic valve (UAV) contributes to regional differences in endothelial nitric oxi...

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Bibliographic Details
Main Authors: Brittany Balint, PhD, Catherine Kollmann, MD, Simon Gauer, MD, Jan M. Federspiel, MD, Hans-Joachim Schäfers, MD, PhD
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:JTCVS Open
Subjects:
aortic valve disease
ascending aorta
aortopathy
unicuspid aortic valve
eNOS
Online Access:http://www.sciencedirect.com/science/article/pii/S2666273621002473

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http://www.sciencedirect.com/science/article/pii/S2666273621002473

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