Cancer prognosis prediction using somatic point mutation and copy number variation data: a comparison of gene-level and pathway-based models

Abstract Background Genomic profiling of solid human tumors by projects such as The Cancer Genome Atlas (TCGA) has provided important information regarding the somatic alterations that drive cancer progression and patient survival. Although researchers have successfully leveraged TCGA data to build...

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Bibliographic Details
Main Authors: Xingyu Zheng, Christopher I. Amos, H. Robert Frost
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Bioinformatics
Online Access:http://link.springer.com/article/10.1186/s12859-020-03791-0