EDP-mitotane in children: reassuring evidence of reversible side-effects and neurotoxicity

Abstract Adrenocortical carcinoma affects one in 5 million children each year. Since prognosis for children older than 4 years is limited, clinicians often choose aggressive treatment with etoposide, doxorubicin, cisplatin (EDP) and mitotane after resection. However, little is known about the impact...

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Bibliographic Details
Main Authors: Rebecca V. Steenaard, Marieke Rutjens, Madeleine H. T. Ettaieb, Max M. van Noesel, Harm R. Haak
Format: Article
Language:English
Published: Springer 2022-04-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-022-00486-1