Breaking through resistance in mCRPC: Enzalutamide analogues as effective anticancer agents for enhanced male survival

To alleviate metastatic castration-resistant prostate cancer (mCRPC), enzalutamide, a non-steroidal antiandrogen, is employed. Following androgen deprivation therapy or anti-androgen treatment, compensatory mechanisms in prostate cancer have been identified, leading to increased expression and funct...

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Bibliographic Details
Main Authors: Ritesh P. Bhole, Payal M. Karche, Shaliendra S. Gurav, Rupesh V. Chikhale
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221171562300382X