IFN-γ inhibitory molecules derived from Eimeria maxima inhibit IL-12 secretion by modulating MAPK pathways in chicken macrophages

IFN-γ inhibitory molecules derived from Eimeria maxima inhibit IL-12 secretion by modulating MAPK pathways in chicken macrophages

ABSTRACT: IFN-γ plays a crucial role in resisting intracellular parasitic protozoa, such as Eimeria species. In our previous study, we identified 4 molecules derived from Eimeria maxima (E. maxima) that significantly inhibited IFN-γ production. However, the mechanism underlying this inhibitory effec...

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Bibliographic Details
Main Authors: Chen Chen, Yufeng Chen, Mingmin Lu, Lixin Xu, Ruofeng Yan, Xiangrui Li, Xiaokai Song
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Poultry Science
Subjects:
chicken coccidia
IFN-γ inhibitory molecules
innate immunity
immune evasion
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579123008799

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http://www.sciencedirect.com/science/article/pii/S0032579123008799

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