Heat stress modulates polymorphonuclear cell response in early pregnancy cows: I. interferon pathway and oxidative stress.

One of the major causes of early pregnancy loss is heat stress. In ruminants, interferon tau (IFNT) is the embryo signal to the mother. Once the interferon signaling pathway is activated, it drives gene expression for interferon-stimulated genes (ISGs) and alters neutrophils responses. The aim of th...

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Bibliographic Details
Main Authors: Carolina Dos Santos Amaral, Gabrielle Rebeca Everling Correa, Lady Katerine Serrano Mujica, Mariani Farias Fiorenza, Suzan Gonçalves Rosa, Cristina Wayne Nogueira, Valério Marques Portela, Fábio Vasconcellos Comim, William Schoenau, Natalia Pavlovna Smirnova, Alfredo Quites Antoniazzi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0257418