Upregulation of OTUD7B (Cezanne) Promotes Tumor Progression via AKT/VEGF Pathway in Lung Squamous Carcinoma and Adenocarcinoma

Upregulation of OTUD7B (Cezanne) Promotes Tumor Progression via AKT/VEGF Pathway in Lung Squamous Carcinoma and Adenocarcinoma

OTUD7B, a multifunctional deubiquitinylase, plays an essential role in inflammation and proliferation signals. However, its function in lung cancer remains largely unknown. The aim of this study was to evaluate the prognostic significance of OTUD7B in patients with lung adenocarcinoma and squamous c...

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Bibliographic Details
Main Authors: Dan-dan Lin, Yang Shen, Shu Qiao, Wen-wen Liu, Lishuang Zheng, Ya-nan Wang, Naipeng Cui, Yun-fan Wang, Shuli Zhao, Jian-hong Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Oncology
Subjects:
OTUD7B
lung squamous carcinoma
lung adenocarcinoma
prognosis
VEGF
Akt
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00862/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00862/full

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