Volume-Associated Clinical and Histopathological Effects of Intranasal Instillation in Syrian Hamsters: Considerations for Infection and Therapeutic Studies

Volume-Associated Clinical and Histopathological Effects of Intranasal Instillation in Syrian Hamsters: Considerations for Infection and Therapeutic Studies

Syrian hamsters are a key animal model of SARS-CoV-2 and other respiratory viruses and are useful for the evaluation of associated medical countermeasures. Delivery of an infectious agent or intervention to the respiratory tract mirrors natural routes of exposure and allows for the evaluation of cli...

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Bibliographic Details
Main Authors: Catalina Forero, Jana M. Ritter, Josilene Nascimento Seixas, JoAnn D. Coleman-McCray, Marie Brake, Jillian A. Condrey, Cassandra Tansey, Stephen R. Welch, Sarah C. Genzer, Jessica R. Spengler
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pathogens
Subjects:
Syrian hamster
animal model
respiratory virus model
intranasal instillation
intranasal inoculation
histopathology
Online Access:https://www.mdpi.com/2076-0817/11/8/898

Internet

https://www.mdpi.com/2076-0817/11/8/898

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