Development of a Genetic Risk Score to predict the risk of overweight and obesity in European adolescents from the HELENA study

Abstract Obesity is the result of interactions between genes and environmental factors. Since monogenic etiology is only known in some obesity-related genes, a genetic risk score (GRS) could be useful to determine the genetic predisposition to obesity. Therefore, the aim of our study was to build a...

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Bibliographic Details
Main Authors: Miguel Seral-Cortes, Sergio Sabroso-Lasa, Pilar De Miguel-Etayo, Marcela Gonzalez-Gross, Eva Gesteiro, Cristina Molina-Hidalgo, Stefaan De Henauw, Frederic Gottrand, Christina Mavrogianni, Yannis Manios, Maria Plada, Kurt Widhalm, Anthony Kafatos, Éva Erhardt, Aline Meirhaeghe, Diego Salazar-Tortosa, Jonatan Ruiz, Luis A. Moreno, Luis Mariano Esteban, Idoia Labayen
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82712-4