Unraveling the epigenetic landscape of pulmonary arterial hypertension: implications for personalized medicine development

Abstract Pulmonary arterial hypertension (PAH) is a multifactorial disease associated with the remodeling of pulmonary blood vessels. If left unaddressed, PAH can lead to right heart failure and even death. Multiple biological processes, such as smooth muscle proliferation, endothelial dysfunction,...

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Bibliographic Details
Main Authors: Jaydev Dave, Vineeta Jagana, Radoslav Janostiak, Malik Bisserier
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-023-04339-5