Chronically infused angiotensin II induces depressive-like behavior via microglia activation

Chronically infused angiotensin II induces depressive-like behavior via microglia activation

Abstract Brain inflammation is one of hypotheses explaining complex pathomechanisms of depression. Angiotensin II (ANGII), which is associated with hypertension, also induces brain inflammation. However, there is no animal study showing the direct relationship between ANGII and depression. To addres...

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Bibliographic Details
Main Authors: Hyun-Sun Park, Min-Jung You, Bohyun Yang, Kyu Beom Jang, Jongman Yoo, Hyun Jin Choi, Sang-Hyuk Lee, Minji Bang, Min-Soo Kwon
Format: Article
Language:English
Published: Nature Portfolio 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79096-2

Internet

https://doi.org/10.1038/s41598-020-79096-2

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