Obesity-related T cell dysfunction impairs immunosurveillance and increases cancer risk

Abstract Obesity is a well-established risk factor for human cancer, yet the underlying mechanisms remain elusive. Immune dysfunction is commonly associated with obesity but whether compromised immune surveillance contributes to cancer susceptibility in individuals with obesity is unclear. Here we u...

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Bibliographic Details
Main Authors: Alexander Piening, Emily Ebert, Carter Gottlieb, Niloufar Khojandi, Lindsey M. Kuehm, Stella G. Hoft, Kelly D. Pyles, Kyle S. McCommis, Richard J. DiPaolo, Stephen T. Ferris, Elise Alspach, Ryan M. Teague
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-47359-5