Pharmacokinetic and pharmacodynamic analyses of terlipressin in patients with hepatorenal syndrome

Pharmacokinetic and pharmacodynamic analyses of terlipressin in patients with hepatorenal syndrome

Abstract The objective of this population pharmacokinetics (PK) analysis was to characterize the PK of terlipressin and its active metabolite, lysine-vasopressin (L-VP), in patients with hepatorenal syndrome (HRS), following intravenous administration of terlipressin 1 mg to 2 mg every 6 h. Sparse P...

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Bibliographic Details
Main Authors: Xiaofeng Wang, Khurram Jamil
Format: Article
Language:English
Published: SpringerOpen 2022-04-01
Series:AAPS Open
Subjects:
Terlipressin
Lysine-vasopressin
Nonlinear mixed-effects modeling
Vasopressin analog
Online Access:https://doi.org/10.1186/s41120-022-00052-7

Internet

https://doi.org/10.1186/s41120-022-00052-7

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