Nuclear factor erythroid 2-related factor 2 agonist protects retinal ganglion cells in glutamate excitotoxicity retinas

Nuclear factor erythroid 2-related factor 2 agonist protects retinal ganglion cells in glutamate excitotoxicity retinas

Objective: To investigate whether tert-Butylhydroquinone (TBHQ) can ameliorate oxidative stress and inflammation induced by glutamate excitotoxicity, and mediate retinal ganglion cell (RGC) damage by activating the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway and inhibiting t...

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Bibliographic Details
Main Authors: Yaqiong An, Haibo Li, Mengxiao Wang, Zhaohua Xia, Lexi Ding, Xiaobo Xia
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
TBHQ
Nrf2
NF-κB
Neuroprotection
Retinal ganglion cell
Glutamate excitotoxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222007673

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http://www.sciencedirect.com/science/article/pii/S0753332222007673

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