Activity-dependent regulation of the cytochrome c promoter in individual hippocampal neurons

The proximal enhancer of the cytochrome c gene (Cycs) contains binding sites for both cAMP response element binding proteins (CREB) and Nuclear Respiratory Factor 1 (NRF1). To investigate how neuronal activity regulates this enhancer region, a lentivirus was constructed in which a short-lived green...

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Bibliographic Details
Main Authors: Jary Y Delgado, Geoffrey eOwens
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2012.00031/full