FOXA1 Regulation Turns Benzamide HDACi Treatment Effect-Specific in BC, Promoting NIS Gene-Mediated Targeted Radioiodine Therapy

FOXA1 Regulation Turns Benzamide HDACi Treatment Effect-Specific in BC, Promoting NIS Gene-Mediated Targeted Radioiodine Therapy

Human sodium iodide symporter (NIS) gene mediated radio-ablation is a successful procedure in thyroid cancer clinics. In recent years, natural expression of NIS is reported in breast cancer (BC) cases but is yet to make its mark as a therapeutic procedure in BC clinics. A pre-exposure to histone dea...

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Bibliographic Details
Main Authors: Maitreyi Rathod, Madhura Kelkar, Snehal Valvi, Girish Salve, Abhijit De
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Oncolytics
Subjects:
sodium iodide symporter
breast cancer
benzamide
HDAC inhibitor
transcriptional factor
radio-iodine therapy, FOXA1
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770520301327

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http://www.sciencedirect.com/science/article/pii/S2372770520301327

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