Nuclear Receptor Nur77 Protects Against Abdominal Aortic Aneurysm by Ameliorating Inflammation Via Suppressing LOX‐1

Nuclear Receptor Nur77 Protects Against Abdominal Aortic Aneurysm by Ameliorating Inflammation Via Suppressing LOX‐1

Background Abdominal aortic aneurysm (AAA) is a life‐threatening vascular disorder characterized by chronic inflammation of the aortic wall, which lacks effective pharmacotherapeutic remedies and has an extremely high mortality. Nuclear receptor NR4A1 (Nur77) functions in various chronic inflammator...

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Bibliographic Details
Main Authors: Hengyuan Zhang, Na Geng, Lingyue Sun, Xinyu Che, Qingqing Xiao, Zhenyu Tao, Long Chen, Yuyan Lyu, Qin Shao, Jun Pu
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
abdominal
angiotensin II
aortic aneurysm
inflammation
macrophage
nuclear receptor
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.121.021707

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.121.021707

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