Fibrinolytic and antibiotic treatment of prosthetic vascular graft infections in a novel rat model.

Fibrinolytic and antibiotic treatment of prosthetic vascular graft infections in a novel rat model.

<h4>Objectives</h4>We developed a rat model of prosthetic vascular graft infection to assess, whether the fibrinolytic tissue plasminogen activator (tPA) could increase the efficacy of antibiotic therapy.<h4>Materials and methods</h4>Rats were implanted a polyethylene graft i...

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Bibliographic Details
Main Authors: Mikkel Illemann Johansen, Søren Jensen Rahbek, Søren Jensen-Fangel, Gabriel Antonio S Minero, Louise Kruse Jensen, Ole Halfdan Larsen, Lise Tornvig Erikstrup, Anders Marthinsen Seefeldt, Lars Østergaard, Rikke Louise Meyer, Nis Pedersen Jørgensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0287671&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0287671&type=printable

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