Myeloid HIF1α Is Involved in the Extent of Orthodontically Induced Tooth Movement

Myeloid HIF1α Is Involved in the Extent of Orthodontically Induced Tooth Movement

During orthodontic tooth movement, transcription factor hypoxia-inducible factor 1α (HIF1α) is stabilised in the periodontal ligament. While HIF1α in periodontal ligament fibroblasts can be stabilised by mechanical compression, in macrophages pressure application alone is not sufficient to stabilise...

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Bibliographic Details
Main Authors: Christian Kirschneck, Nadine Straßmair, Fabian Cieplik, Eva Paddenberg, Jonathan Jantsch, Peter Proff, Agnes Schröder
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomedicines
Subjects:
orthodontic tooth movement
HIF1α
macrophage
µCT
Online Access:https://www.mdpi.com/2227-9059/9/7/796

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https://www.mdpi.com/2227-9059/9/7/796

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