Metabolic disturbances potentially attributable to clogging during continuous renal replacement therapy

Abstract Background Clogging is characterized by a progressive impairment of transmembrane patency in renal replacement devices and occurs due to obstruction of pores by unknown molecules. If citrate-based anti-coagulation is used, clogging can manifest as a metabolic alkalosis accompanied by hypern...

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Main Authors: Mattia M. Müller, Larina Caspar, Onur Sazpinar, Daniel A. Hofmaenner, Rolf Erlebach, Rea Andermatt, Christoph C. Ganter, Reto A. Schuepbach, Pedro D. Wendel-Garcia, Sascha David
Format: Article
Language:English
Published: SpringerOpen 2023-12-01
Series:Intensive Care Medicine Experimental
Subjects:
Online Access:https://doi.org/10.1186/s40635-023-00581-9