Cerebrospinal fluid biomarkers provide evidence for kidney-brain axis involvement in cerebral malaria pathogenesis

Cerebrospinal fluid biomarkers provide evidence for kidney-brain axis involvement in cerebral malaria pathogenesis

IntroductionCerebral malaria is one of the most severe manifestations of malaria and is a leading cause of acquired neurodisability in African children. Recent studies suggest acute kidney injury (AKI) is a risk factor for brain injury in cerebral malaria. The present study evaluates potential mecha...

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Bibliographic Details
Main Authors: Andrea L. Conroy, Dibyadyuti Datta, Robert O. Opoka, Anthony Batte, Paul Bangirana, Adnan Gopinadhan, Kagan A. Mellencamp, Ayse Akcan-Arikan, Richard Idro, Chandy C. John
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Human Neuroscience
Subjects:
cerebral malaria
blood-brain-barrier
cerebrospinal fluid
acute kidney injury
uremia
brain injury
Online Access:https://www.frontiersin.org/articles/10.3389/fnhum.2023.1177242/full

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https://www.frontiersin.org/articles/10.3389/fnhum.2023.1177242/full

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