Control of impulsivity by Gi-protein signalling in layer-5 pyramidal neurons of the anterior cingulate cortex

Control of impulsivity by Gi-protein signalling in layer-5 pyramidal neurons of the anterior cingulate cortex

In order to identify receptors that may serve as therapeutic targets in the treatment of impulse control disorders, van der Veen et al developed a systematic target discovery approach combining behavioural chemogenetics and gene expression analysis. In doing so, they identified Gi-coupled receptors...

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Bibliographic Details
Main Authors: Bastiaan van der Veen, Sampath K. T. Kapanaiah, Kasyoka Kilonzo, Peter Steele-Perkins, Martin M. Jendryka, Stefanie Schulz, Bosiljka Tasic, Zizhen Yao, Hongkui Zeng, Thomas Akam, Janet R. Nicholson, Birgit Liss, Wiebke Nissen, Anton Pekcec, Dennis Kätzel
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02188-w

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https://doi.org/10.1038/s42003-021-02188-w

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