Macromolecular Crowding Is Surprisingly Unable to Deform the Structure of a Model Biomolecular Condensate

The crowded interior of a living cell makes performing experiments on simpler in vitro systems attractive. Although these reveal interesting phenomena, their biological relevance can be questionable. A topical example is the phase separation of intrinsically disordered proteins into biomolecular con...

Full description

Bibliographic Details
Main Authors: Julian C. Shillcock, David B. Thomas, John H. Ipsen, Andrew D. Brown
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/12/2/181