Graph theoretical network analysis, in silico exploration, and validation of bioactive compounds from Cynodon dactylon as potential neuroprotective agents against α-synuclein

Graph theoretical network analysis, in silico exploration, and validation of bioactive compounds from Cynodon dactylon as potential neuroprotective agents against α-synuclein

Introduction: Parkinson's disease (PD) is a chronic, devastating neurodegenerative disorder marked by the death of dopaminergic neurons in the midbrain's substantia nigra pars compacta (Snpc). In alpha-synuclein (α-Syn) self-aggregation, the existence of intracytoplasmic inclusion bodies c...

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Main Authors: Raja Rajeswari Rajeshkumar, Banoth Karan Kumar, Pavadai Parasuraman, Theivendren Panneerselvam, Krishnan Sundar, Damodar Nayak Ammunje, Sureshbabu Ram Kumar Pandian, Sankaranarayanan Murugesan, Shanmugampillai Jeyarajaguru Kabilan, Selvaraj Kunjiappan
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2022-11-01
Series:BioImpacts
Subjects:
α-synuclein
cynodon dactylon
neuroprotective agents
molecular docking
nolecular dynamics
in silico admet
Online Access:https://bi.tbzmed.ac.ir/PDF/bi-12-487.pdf

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https://bi.tbzmed.ac.ir/PDF/bi-12-487.pdf

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