A role for Rap2 in recycling the extended conformation of LFA-1 during T cell migration

Summary T lymphocytes make use of their major integrin LFA-1 to migrate on surfaces that express ICAM-1 such as blood vessels and inflamed tissue sites. How the adhesions are turned over in order to supply traction for this migration has not been extensively investigated. By following the fate of bi...

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Bibliografische gegevens
Hoofdauteurs: Paula Stanley, Sharon Tooze, Nancy Hogg
Formaat: Artikel
Taal:English
Gepubliceerd in: The Company of Biologists 2012-09-01
Reeks:Biology Open
Onderwerpen:
Online toegang:http://bio.biologists.org/content/1/11/1161