CDK4/6 Inhibitors in Hormone Receptor-Positive Metastatic Breast Cancer: Current Practice and Knowledge

Treatment paradigms in advanced hormone receptor (HR)-positive breast cancer were substantially transformed with cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) approval. The addition of these drugs to endocrine treatment profoundly improved progression-free and overall survival. Additionally,...

Full description

Bibliographic Details
Main Authors: Debora de Melo Gagliato, Antonio C Buzaid, Jose Manuel Perez-Garcia, Antonio Llombart, Javier Cortes
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/9/2480