Role of Human Endogenous Retroviral Long Terminal Repeats (LTRs) in Maintaining the Integrity of the Human Germ Line

Retroviruses integrate a reverse transcribed double stranded DNA copy of their viral genome into the chromosomal DNA of cells they infect. Occasionally, exogenous retroviruses infect germ cells and when this happens a profound shift in the virus host dynamic occurs. Retroviruses maintained as heredi...

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Bibliographic Details
Main Authors: Meihong Liu, Maribeth V. Eiden
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/3/6/901/