Role of Human Endogenous Retroviral Long Terminal Repeats (LTRs) in Maintaining the Integrity of the Human Germ Line

Role of Human Endogenous Retroviral Long Terminal Repeats (LTRs) in Maintaining the Integrity of the Human Germ Line

Retroviruses integrate a reverse transcribed double stranded DNA copy of their viral genome into the chromosomal DNA of cells they infect. Occasionally, exogenous retroviruses infect germ cells and when this happens a profound shift in the virus host dynamic occurs. Retroviruses maintained as heredi...

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Bibliographic Details
Main Authors: Meihong Liu, Maribeth V. Eiden
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Series:Viruses
Subjects:
genomic stability
retroelement
primate evolution
Online Access:http://www.mdpi.com/1999-4915/3/6/901/

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