Quantitative phosphoproteomic analysis identifies novel functional pathways of tumor suppressor DLC1 in estrogen receptor positive breast cancer.

Deleted in Liver Cancer-1 (DLC1), a member of the RhoGAP family of proteins, functions as a tumor suppressor in several cancers including breast cancer. However, its clinical relevance is unclear in breast cancer. In this study, expression of DLC1 was correlated with prognosis using publicly availab...

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Bibliographic Details
Main Authors: Yesim Gökmen-Polar, Jason D True, Edyta Vieth, Yuan Gu, Xiaoping Gu, Guihong D Qi, Amber L Mosley, Sunil S Badve
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6168143?pdf=render