Donor regulatory T cells rapidly adapt to recipient tissues to control murine acute graft-versus-host disease
Abstract The adoptive transfer of regulatory T cells is a promising strategy to prevent graft-versus-host disease after allogeneic bone marrow transplantation. Here, we use a major histocompatibility complex-mismatched mouse model to follow the fate of in vitro expanded donor regulatory T cells upon...
Main Authors: | , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-04-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-47575-z |